New paper in Scientific Reports: A computational model of the cerebellar granular layer

New publication from our group out in Scientific Reports (Nature Portfolio).

María P. Tirado, Eva M. Ortigosa, Eduardo Ros, and Jesús A. Garrido present a biologically realistic computational model of the cerebellar granular layer calibrated to experimental data. The model explores the functional impact of synaptic inhibition mediated by Golgi cells and replicates key findings from recent in vivo experiments. The study reveals that moderate inhibition levels optimise pattern separation performance, with feedforward and feedback inhibitory circuits exerting distinct effects on coding expansion and decorrelation.

You can find the full paper in our publications section. Congratulations to all involved!